Brønsted Acidic 1-Ethyl-1,2,4-Trizolium Phenylsulfonate as Catalyst for Biginelli Reaction
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چکیده
منابع مشابه
Facile synthesis of dihydropyrimidinone derivatives via Biginelli reaction using Brønsted acidic ionic liquid [H-NMP]+[CH3SO3]- as an efficient homogeneous catalyst
In this research, a green, operationally simple, highly efficient and facile cascade Biginelli reaction using various aromatic aldehydes, ethyl acetoacetate, and urea/thiourea has been developed. First, the ionic liquid was prepared from the reaction of 1-methyl-2-pyrolidone with methane sulfonic acid. Then, this ionic liquid was applied as an acidic catalyst in the synthesis of dihydropyrimidi...
متن کاملFacile synthesis of dihydropyrimidinone derivatives via Biginelli reaction using Brønsted acidic ionic liquid [H-NMP]+[CH3SO3]- as an efficient homogeneous catalyst
In this research, a green, operationally simple, highly efficient and facile cascade Biginelli reaction using various aromatic aldehydes, ethyl acetoacetate, and urea/thiourea has been developed. First, the ionic liquid was prepared from the reaction of 1-methyl-2-pyrolidone with methane sulfonic acid. Then, this ionic liquid was applied as an acidic catalyst in the synthesis of dihydropyrimidi...
متن کاملAn efficient synthesis of 3,4-Dihydropyrimidin-2(1H)-ones and thiones catalyzed by a novel Brønsted acidic ionic liquid under solvent-free conditions.
We report here an efficient and green method for Biginelli condensation reaction of aldehydes, β-ketoesters and urea or thiourea catalyzed by Brønsted acidic ionic liquid [Btto][p-TSA] under solvent-free conditions. Compared to the classical Biginelli reaction conditions, the present method has the advantages of giving good yields, short reaction times, near room temperature conditions and the ...
متن کاملA rapid one-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using Brønsted-acidic ionic liquid as catalyst.
Pyrido[2,3-d]pyrimidine derivatives were synthesized regioselectivly in good to high yields by one-pot three-component condensation of 6-amino-2-(methylthio)pyrimidin-4(3H)-one, aromatic aldehydes and ethylcyanoacetate or meldrum's acid using 1,2-dimethyl-N-butanesulfonic acid imidazolium hydrogen sulfate ([DMBSI]HSO4) Brønsted-acidic ionic liquid as catalyst. Solvent-free mild reaction conditi...
متن کاملAn Improved Protocol for Biginelli Reaction
Hmim][Tfa] was tested as catalyst for the Biginelli reaction multicomponent reaction under conventional and non conventional heat source i.e. Microwave heating. Low catalyst loading, reduced reaction time and operational simplicity are the main highlights of this proposed protocol. Using our proposed protocol, we tested 30 different biologically active compounds in good yield.
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ژورنال
عنوان ژورنال: Asian Journal of Chemistry
سال: 2018
ISSN: 0970-7077,0975-427X
DOI: 10.14233/ajchem.2018.21373